Laboratory of Structural Biology Research

Software Archive

LSBR is actively developing software for the analysis of electron micrographs and the reconstruction of three-dimensional models of various proteins and protein complexes. The programs are made freely available here in the spirit of collaborating with scientific community involved in three-dimensional electron microscopy.


Software Packages

Links are to documentation and downloadable code (as indicated)

PIC is a software package for 2D image processing.

Responsible person: Benes Trus (CIT/NIH)

The Bsoft package contains many programs used for image processing of electron micrographs, the three-dimensional reconstruction of protein structures, and molecular modeling at different resolution levels.

Responsible person: Bernard Heymann

The PFT2/EM3DR2 programs are used to find the orientations of 2D particle images with respect to a reference (PFT2), and then reconstruct the 3D structure (EM3DR2). These are modified versions of programs that originated from the laboratory of Dr Tim Baker. Key enhancements include the use of a Bsoft front end to facilitate image format access and thebetter encoding of process parameters, as well as numerous improvements in the efficiency of the code.

Responsible person: David Belnap (BYU, Provo, UT)

The Peach distributed processing system is a Perl package designed for running jobs or tasks across multiple platforms.

Responsible person: Bernard Heymann

A program to determine the cyclic symmetry of 2D particle images.
A program to straighten 2D images of filaments.


Questions or problems?
Contact Bernard_Heymann@nih.gov
Updated: 2010-08-04